Your gut microbiome is essential for overall health. We need good bacteria in our gut for immunity, absorption of nutrients from food, protection from pathogens, synthesizing vitamins, creating short-chain fatty acids, and metabolizing bile (to name a few roles).
The word microbiome refers to an ecosystem inhabited by nonhuman microorganisms. The microorganisms of the human microbiome live within the GI tract, vagina, mouth, and skin. We begin “collecting” these friendly bacteria at birth from the vaginal canal, breast milk, and the humans and environments the baby encounters upon arrival in this world. Exposure to these beneficial bacteria at birth is believed to reduce the likelihood of autoimmune disease, diabetes, obesity, and asthma.
The gut microbiome specifically refers to the microbes that reside in the digestive tract.
So what defines a “good” bacteria versus a “bad” bacteria? Bad bacteria are typically ones that are pathogenic and can wreak havoc on our system or even cause illness (i.e., E. coli, Staphylococcus, C. diff, Klebsiella, Lyme, syphilis, etc). These are usually identified as gram-negative bacteria. They are more resistant to antibiotics. The outer membrane contains lipopolysaccharides (LPS), which create inflammation.
Good bacteria include strains of Lactobacillus and Bifidobacterium. These are classified as gram-positive bacteria. Gram-positive bacteria are more susceptible to death with antibiotics and are slower to develop resistance. A balanced microbiome actually consists of about 85% beneficial bacteria to 15% harmful bacteria.
So if we have so many more good bacteria than bad bacteria, how in the world does it become unbalanced? Well, there is a genetic connection to the composition of the gut microbiome. Cystic Fibrosis, Crohn’s Disease, and Ulcerative Colitis have all been shown to have altered microbiome colonization
But there are also factors that are not genetic that can alter the bacteria living in our gut.
Overuse of antibiotics and antibacterial hand sanitizers has decreased our exposure to microbes. Microbes need to come in contact with other microbes to activate good bacteria. If you have taken antibiotics, it not only kills the pathogenic bacteria, but also the beneficial bacteria. If you have not rebuilt your microbiome after antibiotic use, then it is destroyed. Time to build!
The Standard American Diet (SAD) is high in refined grains, oils, and sugars and low in whole grains, legumes, and non-starchy vegetables. Highly processed foods are low in micronutrients. Often, the SAD consists of non-organic produce and conventionally raised meat and seafood. This increases the opportunity to be exposed to GMOs, antibiotics, and hormones. Artificial sugar and sweeteners can also destroy the gut microbiome. And the lack of fiber in the SAD decreases short-chained fatty acid (SCFA), which protects against pathogenic bacteria, gut inflammation, and provides energy for colonocytes. SCFAs are also required for the production of vitamin B12 and vitamin K.
Stress stimulates the sympathetic nervous system. The sympathetic nervous systems put our body into “fight or flight” mode. When this occurs, blood is diverted away from the GI system. Digesting your food when threatened is not going to save you from the mountain lion chasing you. But running and fighting that mountain lion can! If we are constantly in a state of stress, our body is going to have lower microbial diversity. Plus, the increased inflammation can lead to increased permeability of the intestinal lining (leaky gut) and sensitivity to foods
Poor sleep habits can also disrupt the microbiome. Our gut has its own circadian rhythm. It regulates when gastric acid is produced, GI motility, and the release of diurnal defensins (released once a day and defend against bacteria consumed). Bacteria in the gut are also responsible for the production of the neurotransmitters serotonin, dopamine, and GABA. A happy, rested gut equals a happy, healthy you!
Understanding the root cause of the symptoms you might be experiencing is the first step. I recommend taking a deeper dive into your symptoms by getting tested. Functional lab tests provide a roadmap for your wellness journey.
Once we understand the root cause of the symptoms, we can then implement the strategies for restoring gut health.
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